For these reasons PTFE is chemically inert. This means that PTFE can be in continuous contact with a given substance with no detectable chemical reaction taking place. Few chemicals attack PTFE. The reactants are limited to: Violent oxidizers and reducing agents. For example, sodium, in its elemental state, removes fluorine atoms from the PTFE molecule.Other alkali metals such as potassium and lithium.Extreme oxidizers such as fluorine, chlorine trifluoride and related compounds can be handled by PTFE hoses only.